JENOPTIK SYIONS® – Shaping Your Imaging solutiONS

Today’s customers in the field of life science and in vitro diagnostics want complete, flexible workflow systems that can process in vitro samples quickly with a minimum of human error. Researchers and technicians in cell imaging, and molecular diagnostics in the life sciences are looking for high automation in a small footprint. Here’s how to cater to that market.

Providing accessible solutions in novel cell imaging applications

To gain competitive advantage and dominate the market, understanding the goals of the specific cell imaging application is key. This is a challenge if the application is innovative, and by no means established in the marketplace so that users may have time to express their requirements. Time to market becomes a key issue, since there is an inherent advantage in being a recognized pioneer and leader. It’s a matter of timing to launch a highly competent product, beat your rivals to market and win market share. Additionally, it’s a great advantage to be able to develop generations 2 and 3 of your product efficiently, without having to start from scratch every time.

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There are three main considerations that dictate your imaging product design: performance, versatility, and time-to-market. There are fundamental trade-offs among them and clear market trends in instrument design over recent years. Focus on the application, operator independence, a short learning curve, speed from sample to data and consistent results are high on the list of preferences with life science and clinical users.

Finding optimum balance for your life science analytics applications

In every measurement system, there is an inherent trade-off among performance factors. In photonics, it all has to do with the light budget. Take for example the confocal microscope: it is capable of achieving very high optical resolution, and that entails closing the confocal pinhole. Thus, the available light from the sample becomes restricted; this increases the necessary dwell-time on the sample, resulting in slower frame rates and potential photo-damage of the sample.

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Automation, digitalization, miniaturization – integrated digital microscopic imaging enables tailored process automation, designed to suit the application to the fullest. Human error can be reduced, the cost of running the tests falls, precision can be maximized, and you can make automated in vitro diagnostic solutions accessible to labs and users around the world.

If you’re interested in developing next generation sequencing, cytometry, live cell imaging, detection of circulating tumor DNA, amongst many more specific molecular diagnostic applications, then JENOPTIK SYIONS® from Jenoptik is your partner of choice for rapidly constructed, miniaturized optical engines that will fit into any instrument.

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Working directly with your component suppliers, including Jenoptik, is one of the best ways to ensure a smooth CFDA/NMPA approval process for your biomedical device.

When introducing a new biomedical device to a new market, the manufacturer is naturally going to worry about the associated risks. For example: Will our biomedical device get the certifications and approvals it needs?

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Do biomedical device manufacturers really have to write brand-new applications for each national market they enter? Fortunately, for equipment manufacturers, certifications for CFDA, FDA, ISO or MDSAP can be reused now more than ever.

The globalization of the medical device market has led to the proliferation of a veritable alphabet soup of acronyms for the national and international standards-setting agencies that govern such equipment. The paperwork and testing requirements to gain approval from these organizations can seem like a complex, disjointed barrier to manufacturing and selling new products. Do biomedical device manufacturers really have to write brand-new applications for each national market they enter? Fortunately, for biomedical device equipment manufacturers, certifications can be reused now more than ever.

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Gaining CFDA certification for next-generation biomedical devices resembles the processes for approvals from other countries. It’s not as difficult as it sounds.

With more than 1.4 billion people interested in staying healthy, biomedical device manufacturers have golden opportunities in the Chinese market. Hospitals, healthcare organizations and biomedical research laboratories are growing and demanding the same cutting-edge technologies that are found in other countries.

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Traditional microscopes integrated into benchtop instruments are expensive, complicated, need a large amount of lab space, and are loaded with features that are not always required. The JENOPTIK SYIONS® miniaturized digital microscope subsystem focuses on high quality images and versatility, but with a small form factor, ease-of-use, and low cost. As a digital microscope solution in miniature format JENOPTIK SYIONS® consists of inter-compatible modules that work together seamlessly no matter what the final application is. When it comes time to conduct important bioimaging applications, it’s more than a matter of high resolution and sensitive lenses. You need a complete OEM bioimaging solution controlled by software and backed by a team with decades of expertise in light microscopy and digital imaging to advise you and optimize the system to your specific application.

Benefit from Jenoptik´s longstanding experience and expertise in light microscopy and digital imaging

Jenoptik’s technical team has many years of experience with CMOS technology as well as biomedical microscopy and can help you choose new image sensors with the pixel size, resolution, signal-to-noise ratio,dynamic range and other specifications for optimum performance for your particular application.

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CCD or CMOS? Although both devices are built on the same fundamental technology, there are differences that have favored one over the other, depending on the application. Chemiluminescence has often been the reserve of CCD detectors because of their relative sensitivity, but they are slower compared to CMOS. Now, CMOS has taken a great leap, and may be favorable to support the more challenging applications where readout speed, power consumption and portability are of the essence.

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CMOS sensors are very attractive and have such an excellent price-performance ratio that virtually any device today can be equipped with the ability to image – and give any microscope, scientific instrument or medical device a significant competitive advantage. The ability to visualize samples – whether central to the analysis or an apparent “nice to have” feature – can lead to desirable new applications, quality assurance and experimental design.

Biological imaging has evolved from a passive observational collector of descriptive pictures to a keen, versatile and quantitative analytical tool. Microscopic images of tissues and cells provide the basis for characterization and measurements of disease progression, live cell imaging, automated diagnostics, and a host of other activities in the life science and medical diagnostic laboratory. Digital microscopes thus play a crucial role in the signal pathway between the biological sample of interest and the eyes of the scientist.

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